Peptide Impurities and Synthesis Services

We make AAD’s with utmost quality at an affordable cost that can be used as SMs for your peptide API. Having sound experience with AAD’s and other starting material, we also provides quality API with highest possible purity.

Peptide Impurities: Possible impurities during the synthetic process of a therapeutic peptide include Deletion sequences, Incomplete deprotection sequences, Sequence with amino acid modifications, Cleaved sequences and Amino- acid racemization. Some impurities may arise during storage due to degradation mechanisms such as β-elimination and succinimide formation. There are chances of other Impurities like peptide counter ions and trifluoroacetate arise from purification methods or SPPS. The side chain reactions of amino acids from deamidation, oxidation, and hydrolysis reactions result in the formation of impurities. Excipient interactions also generate peptide-related impurities. Well characterized high-quality impurity standards of synthetic peptides are utmost important to judge the quality of the product. At Energon, we can help you with synthesis of impurities with greater purities.